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• Activity deltas table
• Regulatory interactions
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Motif ID: RXR{A,B,G}.p2

Z-value: 1.642

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_-_70288155	26.298	NM_013346	SNX12	sorting nexin 12
chr1_+_6845381	22.955	NM_001195563 NM_001242701 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr17_-_62833225	21.723		PLEKHM1P	pleckstrin homology domain containing, family M (with RUN domain) member 1 pseudogene
chr19_-_1174257	21.269		SBNO2	strawberry notch homolog 2 (Drosophila)
chr14_-_103988829	20.713		CKB	creatine kinase, brain
chr18_-_51750460	18.719		MBD2	methyl-CpG binding domain protein 2
chr8_-_70983549	18.702	NM_024504	PRDM14	PR domain containing 14
chr2_+_230787195	17.197	NM_174899	FBXO36	F-box protein 36
chr14_+_101193275	16.628		DLK1	delta-like 1 homolog (Drosophila)
chr22_+_19701968	16.386	NM_002688	SEPT5	septin 5
chr8_-_70983468	15.633		PRDM14	PR domain containing 14
chr15_+_62682682	15.304		TLN2	talin 2
chr17_-_27278324	15.213		PHF12	PHD finger protein 12
chr14_-_103989195	14.973	NM_001823	CKB	creatine kinase, brain
chr17_-_15902907	14.908	NM_001042697 NM_001042698	ZSWIM7	zinc finger, SWIM-type containing 7
chr19_-_36246411	14.403		HSPB6	heat shock protein, alpha-crystallin-related, B6
chr22_-_44258210	14.246	NM_014351	SULT4A1	sulfotransferase family 4A, member 1
chrX_-_51239426	14.241	NM_018159	NUDT11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr19_-_1174263	14.180	NM_014963	SBNO2	strawberry notch homolog 2 (Drosophila)
chr19_-_14228560	14.143		PRKACA	protein kinase, cAMP-dependent, catalytic, alpha
chr20_-_44539597	14.061	NM_001242921	PLTP	phospholipid transfer protein
chr5_+_149865310	13.948		NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr17_+_3627133	13.838	NM_031965	GSG2	germ cell associated 2 (haspin)
chr16_+_22825806	13.769	NM_006043	HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr15_-_76030958	13.719		DNM1P35	DNM1 pseudogene 35
chr22_-_19511777	13.507		CLDN5	claudin 5
chr16_+_58497993	13.503	NM_001130487	NDRG4	NDRG family member 4
chr1_-_38512446	13.010	NM_002699	POU3F1	POU class 3 homeobox 1
chr2_+_27301693	12.939		EMILIN1	elastin microfibril interfacer 1
chr19_+_7968774	12.781		MAP2K7	mitogen-activated protein kinase kinase 7
chr19_-_14228362	12.471	NM_002730	PRKACA	protein kinase, cAMP-dependent, catalytic, alpha
chr3_+_133465250	12.294		TF	transferrin
chr3_+_133465098	12.277		TF	transferrin
chr3_-_14988976	12.052		LOC100505641	uncharacterized LOC100505641
chr3_+_133465204	11.972		TF	transferrin
chr19_-_56632644	11.915	NM_001002836	ZNF787	zinc finger protein 787
chr3_+_49591897	11.857	NM_003458	BSN	bassoon (presynaptic cytomatrix protein)
chr11_+_118401873	11.616		TMEM25	transmembrane protein 25
chrX_+_38420690	11.548	NM_004615	TSPAN7	tetraspanin 7
chr16_+_58498182	11.386		NDRG4	NDRG family member 4
chr17_+_74733468	11.299	NM_001242532 NM_001242533 NM_001242535 NM_001242536 NM_001242537 NM_024311	MFSD11	major facilitator superfamily domain containing 11
chr17_-_72889704	11.296	NM_178128	FADS6	fatty acid desaturase domain family, member 6
chr20_-_44539542	11.272		PLTP	phospholipid transfer protein
chr14_-_81687265	11.260	NM_015859	GTF2A1	general transcription factor IIA, 1, 19/37kDa
chr19_+_7968762	11.237		MAP2K7	mitogen-activated protein kinase kinase 7
chr3_-_14988939	11.123		LOC100505641	uncharacterized LOC100505641
chr11_+_62439120	11.079	NM_001085372	C11orf83	chromosome 11 open reading frame 83
chr19_-_36246206	11.051		HSPB6	heat shock protein, alpha-crystallin-related, B6
chr6_-_34664517	11.026		C6orf106	chromosome 6 open reading frame 106
chr17_+_38119225	11.024	NM_178171	GSDMA	gasdermin A
chr11_+_62439134	10.959		C11orf83	chromosome 11 open reading frame 83
chr12_-_54982271	10.954	NM_006741	PPP1R1A	protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr19_+_58095507	10.815	NM_001010879	ZIK1	zinc finger protein interacting with K protein 1 homolog (mouse)
chr19_+_7968820	10.574		MAP2K7	mitogen-activated protein kinase kinase 7
chr10_-_81205091	10.542	NM_153367	ZCCHC24	zinc finger, CCHC domain containing 24
chr8_-_57359148	10.488	NM_001135690	PENK	proenkephalin
chr14_+_101193190	10.412	NM_003836	DLK1	delta-like 1 homolog (Drosophila)
chr19_+_50354368	10.345	NM_017432	PTOV1	prostate tumor overexpressed 1
chr19_-_38720312	10.274	NM_001135156	DPF1	D4, zinc and double PHD fingers family 1
chr1_+_202317798	10.198	NM_001167857 NM_001167858 NM_002481	PPP1R12B	protein phosphatase 1, regulatory subunit 12B
chr9_+_74526527	10.182		C9orf85	chromosome 9 open reading frame 85
chr14_-_58764805	10.126		FLJ31306	uncharacterized LOC379025
chr16_+_2653350	10.103		LOC652276	potassium channel tetramerisation domain containing 5 pseudogene
chr19_+_47759730	10.048	NM_015603	CCDC9	coiled-coil domain containing 9
chr19_+_7968765	10.023		MAP2K7	mitogen-activated protein kinase kinase 7
chr19_+_16999871	9.997		F2RL3	coagulation factor II (thrombin) receptor-like 3
chr17_-_4046298	9.975		ZZEF1	zinc finger, ZZ-type with EF-hand domain 1
chr4_-_8873453	9.878	NM_018942	HMX1	H6 family homeobox 1
chr12_-_133532847	9.826	NM_183238 NM_001164715	ZNF605	zinc finger protein 605
chrX_-_17879355	9.814	NM_001172732 NM_001172739 NM_001172743 NM_021785	RAI2	retinoic acid induced 2
chr16_+_22825481	9.688		HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr3_+_133464883	9.686	NM_001063	TF	transferrin
chr22_+_19705891	9.577	NM_001009939	SEPT5	septin 5
chr19_+_7968701	9.554		MAP2K7	mitogen-activated protein kinase kinase 7
chrX_-_51239295	9.525		NUDT11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chrX_+_101380659	9.511	NM_080390	TCEAL2	transcription elongation factor A (SII)-like 2
chr17_+_7554711	9.510		ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr7_+_94023872	9.289	NM_000089	COL1A2	collagen, type I, alpha 2
chr19_+_7968764	9.254	NM_145185	MAP2K7	mitogen-activated protein kinase kinase 7
chr1_+_44412418	9.087	NM_014652	IPO13	importin 13
chr7_+_94024201	9.080		COL1A2	collagen, type I, alpha 2
chr7_+_30068206	8.944		PLEKHA8P1 PLEKHA8	pleckstrin homology domain containing, family A member 8 pseudogene 1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
chr11_+_64067862	8.911	NM_001039496	C11orf20	chromosome 11 open reading frame 20
chr7_-_35734472	8.876		HERPUD2	HERPUD family member 2
chr17_+_7184978	8.814	NM_001042	SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4
chr9_+_103235634	8.747		TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr11_+_113931228	8.736	NM_001018011	ZBTB16	zinc finger and BTB domain containing 16
chr3_-_28390280	8.690		AZI2	5-azacytidine induced 2
chr6_-_132272311	8.686	NM_001901	CTGF	connective tissue growth factor
chr1_+_44412582	8.655		IPO13	importin 13
chr19_+_47759802	8.636		CCDC9	coiled-coil domain containing 9
chr16_+_2039945	8.619	NM_004209	SYNGR3	synaptogyrin 3
chr17_-_62833246	8.607		PLEKHM1P	pleckstrin homology domain containing, family M (with RUN domain) member 1 pseudogene
chr12_+_52345467	8.584		ACVR1B	activin A receptor, type IB
chr7_+_100136845	8.576		AGFG2	ArfGAP with FG repeats 2
chr11_-_118661826	8.575		DDX6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chr11_+_61197574	8.568	NM_017841	SDHAF2	succinate dehydrogenase complex assembly factor 2
chr14_+_101193313	8.562		DLK1	delta-like 1 homolog (Drosophila)
chr10_-_73848263	8.549		SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr7_-_35734728	8.507		HERPUD2	HERPUD family member 2
chr19_+_18723666	8.483	NM_012109	TMEM59L	transmembrane protein 59-like
chr1_-_57888785	8.472		DAB1	disabled homolog 1 (Drosophila)
chr17_-_1532109	8.441	NM_152346	SLC43A2	solute carrier family 43, member 2
chr19_+_50353942	8.305		PTOV1	prostate tumor overexpressed 1
chr6_+_89791510	8.292		PNRC1	proline-rich nuclear receptor coactivator 1
chr5_-_43412417	8.267	NM_148672	CCL28	chemokine (C-C motif) ligand 28
chr19_-_18548971	8.239	NM_001170938 NM_016368	ISYNA1	inositol-3-phosphate synthase 1
chr22_-_51016343	8.222	NM_001145137	CPT1B	carnitine palmitoyltransferase 1B (muscle)
chr9_-_139094886	8.211	NM_014564	LHX3	LIM homeobox 3
chr7_-_35734762	8.208	NM_022373	HERPUD2	HERPUD family member 2
chr7_-_124405029	8.193		GPR37	G protein-coupled receptor 37 (endothelin receptor type B-like)
chr15_+_63569748	8.171	NM_001145646 NM_031301	APH1B	anterior pharynx defective 1 homolog B (C. elegans)
chr17_-_62833264	8.130		PLEKHM1P	pleckstrin homology domain containing, family M (with RUN domain) member 1 pseudogene
chr8_+_27631902	8.098	NM_001017420	ESCO2	establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr6_+_126112057	8.090		NCOA7	nuclear receptor coactivator 7
chr19_+_50354417	8.083		PTOV1	prostate tumor overexpressed 1
chr16_+_55542909	8.041	NM_017839	LPCAT2	lysophosphatidylcholine acyltransferase 2
chr20_+_44657858	8.040		SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chr22_-_29784568	8.012	NM_001127 NM_001166019 NM_145730	AP1B1	adaptor-related protein complex 1, beta 1 subunit
chr1_-_156399183	7.955	NM_006365	C1orf61	chromosome 1 open reading frame 61
chr6_+_35227478	7.935	NM_003427	ZNF76	zinc finger protein 76
chr2_+_241938254	7.913	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr3_-_139258531	7.903	NM_001130992 NM_001130993 NM_002899	RBP1	retinol binding protein 1, cellular
chr1_+_44412640	7.886		IPO13	importin 13
chr6_+_43738757	7.804		VEGFA	vascular endothelial growth factor A
chr5_+_74807580	7.779	NM_016218	POLK	polymerase (DNA directed) kappa
chr16_+_69984809	7.746	NM_182619	CLEC18C CLEC18A	C-type lectin domain family 18, member C C-type lectin domain family 18, member A
chr3_-_28390506	7.723	NM_001134432 NM_001134433 NM_022461	AZI2	5-azacytidine induced 2
chr22_-_29784430	7.711		AP1B1	adaptor-related protein complex 1, beta 1 subunit
chr11_+_62380212	7.710	NM_000327	ROM1	retinal outer segment membrane protein 1
chrY_-_15591799	7.695		UTY	ubiquitously transcribed tetratricopeptide repeat gene, Y-linked
chr16_+_58497628	7.694		NDRG4	NDRG family member 4
chr17_-_1531543	7.683		SLC43A2	solute carrier family 43, member 2
chr12_-_53448167	7.673		LOC283335	uncharacterized LOC283335
chr12_-_48152180	7.649	NM_001098532 NM_006105	RAPGEF3	Rap guanine nucleotide exchange factor (GEF) 3
chr17_+_42264300	7.642	NM_001076674 NM_024107	TMUB2	transmembrane and ubiquitin-like domain containing 2
chr11_-_2162340	7.596	NM_001127598	IGF2	insulin-like growth factor 2 (somatomedin A)
chr10_-_26986553	7.586
chr3_-_14989399	7.542		LOC100505641	uncharacterized LOC100505641
chr15_-_71146427	7.526	NM_018357 NM_197958	LARP6	La ribonucleoprotein domain family, member 6
chr9_-_110251754	7.446		KLF4	Kruppel-like factor 4 (gut)
chr22_-_19512001	7.440		CLDN5	claudin 5
chr20_+_44657812	7.413	NM_020708	SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chr16_+_70148213	7.379		PDPR	pyruvate dehydrogenase phosphatase regulatory subunit
chr22_+_24373107	7.377	NM_001144931	LOC391322	D-dopachrome tautomerase-like
chr9_-_133454818	7.375		LOC100272217	uncharacterized LOC100272217
chr9_+_103235489	7.364	NM_003692	TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr3_-_48885028	7.348		PRKAR2A	protein kinase, cAMP-dependent, regulatory, type II, alpha
chr17_+_42264582	7.327		TMUB2	transmembrane and ubiquitin-like domain containing 2
chr7_+_97910978	7.304	NM_001159491 NM_015379	BRI3	brain protein I3
chr6_-_46459010	7.293	NM_001251974	RCAN2	regulator of calcineurin 2
chr2_+_105471745	7.284	NM_006236	POU3F3	POU class 3 homeobox 3
chr22_+_19705990	7.244		SEPT5-GP1BB	SEPT5-GP1BB readthrough
chr14_-_103989112	7.195		CKB	creatine kinase, brain
chr19_+_56186426	7.182	NM_001130072 NM_013333	EPN1	epsin 1
chr17_+_72920369	7.138	NM_178160	OTOP2	otopetrin 2
chr19_-_49658645	7.073	NM_002152	HRC	histidine rich calcium binding protein
chr11_-_118661856	7.070		DDX6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chr3_+_50306578	7.050		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr12_+_58013692	7.048	NM_133489	SLC26A10	solute carrier family 26, member 10
chr19_-_4723791	7.037		DPP9	dipeptidyl-peptidase 9
chr8_-_26371387	7.000	NM_007257	PNMA2	paraneoplastic antigen MA2
chr7_-_3083346	6.922	NM_032415	CARD11	caspase recruitment domain family, member 11
chrX_+_55478537	6.824	NM_014061	MAGEH1	melanoma antigen family H, 1
chr2_+_27274520	6.823		AGBL5	ATP/GTP binding protein-like 5
chr14_+_29236882	6.808		FOXG1	forkhead box G1
chr20_-_23402038	6.766	NM_022080	NAPB	N-ethylmaleimide-sensitive factor attachment protein, beta
chr22_-_20104695	6.757		TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr11_+_125774271	6.754	NM_013264	DDX25	DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr17_-_4046190	6.731
chr11_+_450346	6.715		PTDSS2	phosphatidylserine synthase 2
chr14_-_21493910	6.699	NM_016250 NM_201535 NM_201536 NM_201537	NDRG2	NDRG family member 2
chr17_-_46688279	6.671		HOXB7	homeobox B7
chr17_+_42264573	6.664	NM_177441	TMUB2	transmembrane and ubiquitin-like domain containing 2
chr2_-_103353300	6.657	NM_032718	MFSD9	major facilitator superfamily domain containing 9
chrX_+_135229536	6.652	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr1_+_7844713	6.610	NM_016831	PER3	period homolog 3 (Drosophila)
chr19_+_39390570	6.598		NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr13_+_37006628	6.589		CCNA1	cyclin A1
chr20_+_44650260	6.585	NM_001134771	SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chr22_-_51021200	6.585		CHKB	choline kinase beta
chr19_-_39390168	6.578	NM_012237 NM_001193286 NM_030593	SIRT2	sirtuin 2
chr12_-_42631982	6.575	NM_001190977	YAF2	YY1 associated factor 2
chr11_+_450260	6.571	NM_030783	PTDSS2	phosphatidylserine synthase 2
chr16_+_58497548	6.565	NM_020465	NDRG4	NDRG family member 4
chr19_-_18548788	6.546	NM_001170939	ISYNA1	inositol-3-phosphate synthase 1
chr22_-_20104745	6.535	NM_022727 NM_182984	TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr1_+_183774214	6.533		RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr6_+_117002349	6.527	NM_002269	KPNA5	karyopherin alpha 5 (importin alpha 6)
chr14_-_23834417	6.523		EFS	embryonal Fyn-associated substrate
chr1_+_19971865	6.517	NM_001204085	NBL1	neuroblastoma, suppression of tumorigenicity 1
chr19_+_45754551	6.498		MARK4	MAP/microtubule affinity-regulating kinase 4
chr19_+_52873169	6.483	NM_001145434	ZNF880	zinc finger protein 880
chr5_+_173472692	6.481	NM_015980	HMP19	HMP19 protein
chr19_-_6279797	6.438
chr22_+_38035718	6.428		SH3BP1	SH3-domain binding protein 1
chr8_+_26371461	6.408	NM_001197293	DPYSL2	dihydropyrimidinase-like 2
chr19_-_12595625	6.391	NM_152601	ZNF709	zinc finger protein 709
chr11_-_118661898	6.365	NM_004397	DDX6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chr10_-_75910525	6.332	NM_012095 NM_207012	AP3M1	adaptor-related protein complex 3, mu 1 subunit

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.51	8.72e-20	GO:0048856	anatomical structure development
1.43	3.42e-18	GO:0032502	developmental process
1.51	1.01e-17	GO:0048731	system development
1.75	4.24e-17	GO:0009653	anatomical structure morphogenesis
1.24	7.30e-17	GO:0065007	biological regulation
1.44	2.60e-16	GO:0007275	multicellular organismal development
1.15	1.52e-15	GO:0009987	cellular process
1.40	6.16e-15	GO:0023052	signaling
1.56	1.34e-13	GO:0030154	cell differentiation
1.24	2.67e-13	GO:0050794	regulation of cellular process
1.23	3.48e-13	GO:0050789	regulation of biological process
1.53	7.38e-13	GO:0048869	cellular developmental process
1.65	7.94e-13	GO:0007399	nervous system development
1.29	2.20e-12	GO:0032501	multicellular organismal process
1.60	5.14e-12	GO:0023051	regulation of signaling
1.67	2.11e-11	GO:0051239	regulation of multicellular organismal process
1.79	9.60e-11	GO:0050793	regulation of developmental process
1.36	1.09e-10	GO:0007165	signal transduction
1.76	8.81e-10	GO:0048468	cell development
1.84	1.33e-09	GO:2000026	regulation of multicellular organismal development
1.49	2.44e-09	GO:0048513	organ development
1.58	3.23e-09	GO:0009966	regulation of signal transduction
1.73	7.15e-09	GO:0022008	neurogenesis
1.75	7.63e-09	GO:0048699	generation of neurons
1.29	8.30e-09	GO:0051716	cellular response to stimulus
1.87	1.50e-08	GO:0007167	enzyme linked receptor protein signaling pathway
1.66	1.77e-08	GO:0010646	regulation of cell communication
1.68	2.07e-08	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.82	6.71e-08	GO:0045595	regulation of cell differentiation
1.46	7.61e-08	GO:0048583	regulation of response to stimulus
1.80	8.14e-08	GO:0030182	neuron differentiation
1.98	1.34e-07	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.41	2.66e-07	GO:0006355	regulation of transcription, DNA-dependent
1.63	3.23e-07	GO:0007154	cell communication
1.35	5.08e-07	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35	5.08e-07	GO:0031326	regulation of cellular biosynthetic process
1.35	6.04e-07	GO:0009889	regulation of biosynthetic process
1.35	7.46e-07	GO:0048518	positive regulation of biological process
1.36	7.95e-07	GO:0010468	regulation of gene expression
1.72	1.04e-06	GO:0007267	cell-cell signaling
1.36	1.51e-06	GO:0048522	positive regulation of cellular process
1.81	1.64e-06	GO:0009887	organ morphogenesis
1.38	2.26e-06	GO:0051252	regulation of RNA metabolic process
1.39	2.28e-06	GO:0048523	negative regulation of cellular process
1.82	2.43e-06	GO:0048666	neuron development
1.74	3.32e-06	GO:0010628	positive regulation of gene expression
2.03	3.57e-06	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
2.10	4.01e-06	GO:0051093	negative regulation of developmental process
1.35	4.47e-06	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.36	4.98e-06	GO:0048519	negative regulation of biological process
1.78	5.09e-06	GO:0000902	cell morphogenesis
2.76	6.62e-06	GO:0001503	ossification
1.63	7.02e-06	GO:0006351	transcription, DNA-dependent
1.88	8.04e-06	GO:0072358	cardiovascular system development
1.88	8.04e-06	GO:0072359	circulatory system development
1.84	1.08e-05	GO:0000904	cell morphogenesis involved in differentiation
2.07	1.18e-05	GO:0001501	skeletal system development
1.74	1.29e-05	GO:0032989	cellular component morphogenesis
1.27	1.37e-05	GO:0080090	regulation of primary metabolic process
1.32	1.38e-05	GO:0051171	regulation of nitrogen compound metabolic process
1.27	1.56e-05	GO:0031323	regulation of cellular metabolic process
1.90	1.63e-05	GO:0032583	regulation of gene-specific transcription
2.08	1.65e-05	GO:0022603	regulation of anatomical structure morphogenesis
1.34	1.74e-05	GO:0010556	regulation of macromolecule biosynthetic process
1.57	2.01e-05	GO:0032879	regulation of localization
1.28	2.07e-05	GO:0060255	regulation of macromolecule metabolic process
1.25	2.08e-05	GO:0019222	regulation of metabolic process
1.81	2.50e-05	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.56	2.71e-05	GO:0009605	response to external stimulus
1.35	3.81e-05	GO:0042221	response to chemical stimulus
1.95	3.94e-05	GO:0048598	embryonic morphogenesis
1.86	4.30e-05	GO:0048812	neuron projection morphogenesis
1.71	5.45e-05	GO:0045893	positive regulation of transcription, DNA-dependent
1.81	5.77e-05	GO:0031175	neuron projection development
1.67	5.98e-05	GO:0009790	embryo development
1.85	6.12e-05	GO:0051094	positive regulation of developmental process
1.71	7.69e-05	GO:0010629	negative regulation of gene expression
1.58	8.44e-05	GO:0009888	tissue development
1.85	8.77e-05	GO:0048667	cell morphogenesis involved in neuron differentiation
1.63	9.45e-05	GO:0010557	positive regulation of macromolecule biosynthetic process
1.78	1.03e-04	GO:0032990	cell part morphogenesis
1.26	1.05e-04	GO:0051179	localization
1.74	1.19e-04	GO:0051253	negative regulation of RNA metabolic process
2.50	1.35e-04	GO:0001655	urogenital system development
1.77	1.38e-04	GO:0048858	cell projection morphogenesis
2.09	1.53e-04	GO:0045596	negative regulation of cell differentiation
1.74	1.71e-04	GO:0045892	negative regulation of transcription, DNA-dependent
1.17	1.72e-04	GO:0050896	response to stimulus
1.75	2.33e-04	GO:0007417	central nervous system development
1.58	2.62e-04	GO:0051128	regulation of cellular component organization
1.96	3.36e-04	GO:0060284	regulation of cell development
1.93	3.50e-04	GO:0007411	axon guidance
1.77	4.87e-04	GO:0048646	anatomical structure formation involved in morphogenesis
1.63	5.09e-04	GO:0009719	response to endogenous stimulus
1.42	5.56e-04	GO:0035556	intracellular signal transduction
2.02	6.75e-04	GO:0001568	blood vessel development
1.64	7.26e-04	GO:0030030	cell projection organization
1.80	7.50e-04	GO:0007409	axonogenesis
1.36	7.70e-04	GO:0007166	cell surface receptor linked signaling pathway
1.50	1.05e-03	GO:0032774	RNA biosynthetic process
1.64	1.13e-03	GO:0009725	response to hormone stimulus
1.64	1.13e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.11	1.21e-03	GO:0048514	blood vessel morphogenesis
1.53	1.27e-03	GO:0040011	locomotion
1.93	1.30e-03	GO:0051130	positive regulation of cellular component organization
2.09	1.40e-03	GO:0048011	nerve growth factor receptor signaling pathway
2.40	1.45e-03	GO:0050678	regulation of epithelial cell proliferation
1.94	1.62e-03	GO:0001944	vasculature development
1.31	1.77e-03	GO:0065008	regulation of biological quality
1.59	1.81e-03	GO:0031327	negative regulation of cellular biosynthetic process
2.34	1.88e-03	GO:0045165	cell fate commitment
1.62	2.07e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
1.59	2.17e-03	GO:0051254	positive regulation of RNA metabolic process
1.52	2.20e-03	GO:0009891	positive regulation of biosynthetic process
1.52	2.47e-03	GO:0031328	positive regulation of cellular biosynthetic process
2.57	2.68e-03	GO:0048736	appendage development
2.57	2.68e-03	GO:0060173	limb development
1.73	2.74e-03	GO:0010648	negative regulation of cell communication
1.78	2.84e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.61	2.91e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.54	3.34e-03	GO:0072001	renal system development
2.58	3.64e-03	GO:0035107	appendage morphogenesis
2.58	3.64e-03	GO:0035108	limb morphogenesis
1.25	3.78e-03	GO:0051234	establishment of localization
1.25	3.93e-03	GO:0006810	transport
3.21	4.02e-03	GO:0010810	regulation of cell-substrate adhesion
1.90	4.16e-03	GO:0051270	regulation of cellular component movement
1.53	4.21e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.54	4.46e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.72	4.89e-03	GO:0023057	negative regulation of signaling
1.99	4.98e-03	GO:0040007	growth
1.56	5.11e-03	GO:0009890	negative regulation of biosynthetic process
1.23	5.24e-03	GO:0016043	cellular component organization
2.22	5.72e-03	GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter
1.82	7.10e-03	GO:0032535	regulation of cellular component size
1.57	7.59e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.93	7.80e-03	GO:0030334	regulation of cell migration
1.73	8.03e-03	GO:0009968	negative regulation of signal transduction
1.88	8.13e-03	GO:0040012	regulation of locomotion
1.78	8.35e-03	GO:0007420	brain development
2.58	8.39e-03	GO:0030198	extracellular matrix organization
1.81	8.89e-03	GO:0045597	positive regulation of cell differentiation
2.34	1.11e-02	GO:0022604	regulation of cell morphogenesis
1.91	1.14e-02	GO:2000145	regulation of cell motility
1.64	1.31e-02	GO:0019226	transmission of nerve impulse
1.64	1.31e-02	GO:0035637	multicellular organismal signaling
2.57	1.43e-02	GO:0051216	cartilage development
2.47	1.46e-02	GO:0001822	kidney development
1.90	1.55e-02	GO:0008361	regulation of cell size
2.30	1.61e-02	GO:0048705	skeletal system morphogenesis
1.40	1.64e-02	GO:0010604	positive regulation of macromolecule metabolic process
2.78	1.81e-02	GO:2000027	regulation of organ morphogenesis
1.67	1.82e-02	GO:0046903	secretion
3.25	2.07e-02	GO:0001649	osteoblast differentiation
2.18	2.08e-02	GO:0043062	extracellular structure organization
2.99	2.39e-02	GO:0050680	negative regulation of epithelial cell proliferation
5.99	2.61e-02	GO:0051893	regulation of focal adhesion assembly
5.99	2.61e-02	GO:0090109	regulation of cell-substrate junction assembly
2.28	2.65e-02	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.84	2.83e-02	GO:0035295	tube development
1.50	2.98e-02	GO:0051049	regulation of transport
2.52	3.02e-02	GO:0030326	embryonic limb morphogenesis
2.52	3.02e-02	GO:0035113	embryonic appendage morphogenesis
1.91	3.14e-02	GO:0006897	endocytosis
1.91	3.14e-02	GO:0010324	membrane invagination
2.07	3.30e-02	GO:0030900	forebrain development
1.78	3.38e-02	GO:0032870	cellular response to hormone stimulus
1.60	3.66e-02	GO:0006935	chemotaxis
1.60	3.66e-02	GO:0042330	taxis
1.20	3.70e-02	GO:0071840	cellular component organization or biogenesis
1.75	3.73e-02	GO:0071495	cellular response to endogenous stimulus
2.50	3.74e-02	GO:0040013	negative regulation of locomotion
1.42	4.15e-02	GO:0042127	regulation of cell proliferation
1.70	4.16e-02	GO:0051056	regulation of small GTPase mediated signal transduction
1.60	4.38e-02	GO:0048585	negative regulation of response to stimulus
1.64	4.46e-02	GO:0007268	synaptic transmission
1.68	4.70e-02	GO:0007264	small GTPase mediated signal transduction

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.39	5.66e-08	GO:0044459	plasma membrane part
1.90	3.37e-06	GO:0045202	synapse
1.44	5.01e-05	GO:0031226	intrinsic to plasma membrane
1.81	8.68e-05	GO:0043005	neuron projection
1.43	1.32e-04	GO:0005887	integral to plasma membrane
1.79	2.97e-04	GO:0031012	extracellular matrix
1.41	1.29e-03	GO:0000267	cell fraction
2.12	2.59e-03	GO:0030136	clathrin-coated vesicle
1.46	3.60e-03	GO:0005626	insoluble fraction
1.96	5.44e-03	GO:0030135	coated vesicle
2.31	6.04e-03	GO:0044420	extracellular matrix part
2.70	7.43e-03	GO:0005604	basement membrane
1.43	8.03e-03	GO:0042995	cell projection
1.73	8.76e-03	GO:0005578	proteinaceous extracellular matrix
1.44	1.33e-02	GO:0031982	vesicle
1.96	1.43e-02	GO:0031252	cell leading edge
1.43	1.92e-02	GO:0031410	cytoplasmic vesicle
1.44	1.92e-02	GO:0031988	membrane-bounded vesicle
1.42	1.95e-02	GO:0005624	membrane fraction
1.72	2.19e-02	GO:0044456	synapse part
1.43	3.45e-02	GO:0016023	cytoplasmic membrane-bounded vesicle
1.63	3.70e-02	GO:0048471	perinuclear region of cytoplasm
3.24	3.76e-02	GO:0005581	collagen

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.68	1.42e-09	GO:0001071	nucleic acid binding transcription factor activity
1.68	1.42e-09	GO:0003700	sequence-specific DNA binding transcription factor activity
1.76	1.02e-07	GO:0043565	sequence-specific DNA binding
1.56	2.58e-06	GO:0030528	transcription regulator activity
1.15	2.78e-05	GO:0005515	protein binding
2.92	2.27e-04	GO:0005201	extracellular matrix structural constituent
1.29	3.64e-04	GO:0003677	DNA binding
1.07	7.48e-04	GO:0005488	binding
1.81	2.20e-03	GO:0016563	transcription activator activity
3.16	2.37e-03	GO:0004879	ligand-dependent nuclear receptor activity
3.17	4.10e-03	GO:0003707	steroid hormone receptor activity
2.43	7.47e-03	GO:0005057	receptor signaling protein activity
1.96	7.84e-03	GO:0000975	regulatory region DNA binding
1.96	7.84e-03	GO:0001067	regulatory region nucleic acid binding
1.96	7.84e-03	GO:0044212	transcription regulatory region DNA binding
2.09	8.29e-03	GO:0005085	guanyl-nucleotide exchange factor activity
3.19	1.23e-02	GO:0046332	SMAD binding
1.73	2.78e-02	GO:0005083	small GTPase regulator activity
1.71	3.20e-02	GO:0016564	transcription repressor activity
1.90	3.28e-02	GO:0010843	promoter binding
2.37	3.51e-02	GO:0005088	Ras guanyl-nucleotide exchange factor activity
1.56	3.68e-02	GO:0060589	nucleoside-triphosphatase regulator activity
5.72	3.90e-02	GO:0048185	activin binding
1.56	4.41e-02	GO:0030695	GTPase regulator activity
1.60	4.41e-02	GO:0022838	substrate-specific channel activity
1.60	4.82e-02	GO:0005216	ion channel activity